000 males with nonmetastatic prostate cancer.
The researchers used medical information extracted from the UK Clinical Practice Analysis Datalink linked to the Hospital Episodes Statistics database. The study included men newly identified as having nonmetastatic prostate malignancy between January 1997 and December 2008 who had been followed up until December 2009. Situations were patients with incident AKI during follow-up who were matched with up to 20 controls on age randomly, twelve months of prostate cancer diagnosis, and duration of follow-up. Evaluation was executed to estimate the odds ratios of AKI associated with the use of ADT. ADT was categorized into 1 of 6 mutually exclusive groupings: gonadotropin-releasing hormone agonists, oral antiandrogens, combined androgen blockade, bilateral orchiectomy, estrogens, and mix of the above.Additionally, two patients without cirrhosis discontinued treatment due to adverse events. GIFT-I included a placebo-controlled arm and studied patients with and without compensated cirrhosis, who were not used to therapy or treatment-experienced . Related StoriesMylan announces U.S. Release of generic Fusilev for InjectionNovo Nordisk announces FDA acceptance of Tresiba for diabetes treatmentAllergan settles patent litigation with Amneal linked to NAMENDA XR extended release capsules’We are pleased to announce the regulatory submission of our two direct-acting hepatitis C antiviral treatment in Japan, which comes after on quickly from recent approvals of our three direct-acting antiviral treatment in the U.S., Canada and the European Union,’ stated Scott Brun, M.D., vice president, pharmaceutical advancement, AbbVie.